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PAHO Epidemiological Avian Influenza A(H5N1) in the Americas Region 15 Oct 2025

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"The summary of the situation in the Americas Region:

Since 2022 and as of epidemiological week (EW) 41 of 2025, a total of 19 countries and territories2 in the Americas Region reported 5,063 outbreaks3 of avian influenza A(H5N1) to WOAH (3), representing 115 additional outbreaks since the last epidemiological update on avian influenza A(H5N1) published by the Pan American Health Organization/World Health Organization (PAHO/WHO) on 15 May 2025 (3, 5).

Between 2022 and 14 October 2025, a total of 76 human infections caused by avian influenza A(H5), including two deaths, have been reported in five countries in the Americas, with one additional case since the last epidemiological update on avian influenza A(H5N1) published by PAHO/WHO on 15 May 2025 (Figure 1) (5-7). The most recent case of human infection with avian influenza A(H5) reported in the Americas Region was recorded in Mexico on 2 October 2025 (6, 7), in addition to the case reported in Mexico on 2 April 2025 (8-10). The remaining cases are distributed as follows: 71 cases in the United States of America—one in 2022 and 70 since 2024 (11), one case in Canada confirmed on 13 November 2024 (12), one case in Chile reported on 29 March 2023 (13), and one case in Ecuador reported on 9 January 2023 (14)."

pan american health organization
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influenza a
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human cases