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Invited review: The One Health challenges and opportunities of the H5N1 outbreak in dairy cattle in the United States

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Lombard et al. (2025) summarized the situation of the H5N1 outbreak in dairy cattle in the US. The authors reviewed:

  1. How is H5N1 affecting the safety and availability of the US food supply?
  2. How is H5N1 virus being transmitted among dairy cattle?
  3. What components of the dairy ecosystem support H5N1 and [bovine influenza A] BIA?
  4. What have the impacts of this outbreak been on the US dairy and poultry sectors?
  5. What are the human health impacts of H5N1 in the United States?
  6. What is the pandemic potential of H5N1 clade 2.3.4.4b genotype B3.13?
  7. Addressing H5N1 in the dairy industry