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Genotype B3.13 influenza A(H5N1) viruses isolated from dairy cattle demonstrate high virulence in laboratory models, but retain avian virus-like properties

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Fabrizio et al. (2025) stated that, "While 2.3.4.4b viruses induce severe disease in mammalian models, they retain many avian virus-like characteristics." and concluded: "Based on the data generated through this assessment, the risk to human health posed by the bovine A(H5N1) viruses in their current form is low, especially for those not exposed to dairy cows, their raw milk, or culling infected poultry flocks."