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Interim Guidance on Influenza Antiviral Post-exposure Prophylaxis of Persons Exposed to Birds or Other Animals with Novel Influenza A Viruses Associated with Severe Human Disease or with the Potential to Cause Severe Human Disease

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The CDC published a guidance document for clinicians caring for persons that had exposure to novel influenza A viruses. Some interesting notes:

  • Novel influenza A viruses include highly pathogenic avian influenza A(H5N1), A(H5N6) and avian influenza A(H7N9)
  • These are highlighted because they have been associated with severe human disease or because there is limited data on disease severity.
  • Recent exposure is within 10 days.
  • Close exposure is defined as being within approximately 6 feet of birds or other animals with confirmed novel influenza A viruses.
  • Exposures are defined: handling, culling, consuming uncooked food including raw milk, direct contact with contaminated surfaces, visiting and working at locations with animals confirmed influenza A virus infections, etc. CDC information for people exposed
  • Persons exposed should monitor themselves for 10 days.
  • New illness symptoms particularly respiratory symptoms, conjunctivitis or other symptoms, with or without fever should be tested.
  • Clinicians are directed to treat with oral oseltamivir twice daily rather than the once a daily dosage for seasonal influenza.