The National Enteric Surveillance Program (NESP) is a collaborative program between the Public Health Agency of Canada (PHAC) and the Provincial Public Health Laboratories. Through NESP, weekly analysis and reporting is conducted for 14 different organisms causing enteric illness, including 10 which are nationally notifiable. The data derived from this surveillance system supports detection of multi-provincial clusters and outbreaks, guides public health interventions, and are designed to integrate with national and international efforts to limit the transmission of enteric diseases.